2种气密性测试方法在高等级生物安全实验室围护结构测试过程中的关联性探讨及研究
Discussion and research on correlation of two air tightness testing methods in high-level biosafety laboratory envelope air tightness tests
摘要：
分别使用压力衰减法和恒压法对高等级生物安全实验室围护结构进行了气密性测试，并对测试结果进行了理论计算及对比分析。结果表明：就同一受试对象而言，对于固定时间内通过压力衰减法计算所得的气密性测试结果，始终存在按照某一等效压差进行的恒压法测试结果与其相对应，但受仪器测试精度、环境温度、测试对象体积影响，2种方法实测泄漏率结果存在一定差异；就检测方法而言，2种方法之间并不存在哪种方法更严格的情况；就测试结果而言，在明确压力衰减法评价标准及保证受试对象体积准确的前提下，如使用恒压法按照流动指数近似为1.0确定的等效压差进行气密性测试得到的结果能够满足评价标准，则压力衰减法测试结果必然能够满足对应评价标准。
Abstract：
In this paper, the pressure decay method and constant pressure method are used respectively to test the air tightness of the envelope in the high-level biosafety laboratory, and the test results are calculated and analysed theoretically.The results shows that for the same test object, for the air tightness calculated by the pressure decay method in a fixed time, there is always a corresponding constant pressure test result based on a certain equivalent pressure difference. However, due to the influence of instrument precision, ambient temperature and test object volume, there are some differences in the leakage rate measured by the two methods. In terms of detection methods, there is no more stringent case between the two methods. In terms of test results, under the premise of clear evaluation criteria of pressure decay method and accurate volume of test objects, if the air tightness test results can meet the evaluation criteria by using constant pressure method and equivalent pressure difference determined by flow index approximately 1.0, the test results of pressure decay method will certainly meet the corresponding evaluation criteria.
Keywords:high-level biosafety laboratory; envelope structure; air tightness; pressure decay method; constant pressure method; equivalent leakage; equivalent differential pressure